Lion's Mane Research

Cognitive function:

• Improvement of cognitive functions by oral intake of Hericium erinaceus

 https://pubmed.ncbi.nlm.nih.gov/31413233/

• Therapeutic potential of culinary-medicinal mushrooms for the management of neurodegenerative diseases: diversity, metabolite, and mechanism

 https://pubmed.ncbi.nlm.nih.gov/24654802/

• Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial

 https://pubmed.ncbi.nlm.nih.gov/18844328/

Depression and anxiety:

• Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake

 https://pubmed.ncbi.nlm.nih.gov/20834180/

• Therapeutic Potential of Hericium erinaceus for Depressive Disorder

 https://pubmed.ncbi.nlm.nih.gov/31881712/

• Neurogenesis-dependent antidepressant-like activity of Hericium erinaceus in an animal model of depression

 https://pubmed.ncbi.nlm.nih.gov/34876186/

Neurogenesis:

• Hericium erinaceus Improves Recognition Memory and Induces Hippocampal and Cerebellar Neurogenesis in Frail Mice during Aging

 https://pubmed.ncbi.nlm.nih.gov/30934760/

• Neurogenesis-dependent antidepressant-like activity of Hericium erinaceus in an animal model of depression

 https://pubmed.ncbi.nlm.nih.gov/34876186/

• Hericium erinaceus Extract Reduces Anxiety and Depressive Behaviors by Promoting Hippocampal Neurogenesis in the Adult Mouse Brain

 https://pubmed.ncbi.nlm.nih.gov/29091526/

Gut health:

• Value added immunoregulatory polysaccharides of Hericium erinaceus and their effect on the gut microbiota

 https://pubmed.ncbi.nlm.nih.gov/33838836/

• Extracts from Hericium erinaceus relieve inflammatory bowel disease by regulating immunity and gut microbiota

 https://pubmed.ncbi.nlm.nih.gov/29156761/

• Influence of Short-Term Consumption of Hericium erinaceus on Serum Biochemical Markers and the Changes of the Gut Microbiota: A Pilot Study

https://pubmed.ncbi.nlm.nih.gov/33800983/

Inflammation:

• Neuroprotective Metabolites of Hericium erinaceus Promote Neuro-Healthy Aging

 https://pubmed.ncbi.nlm.nih.gov/34203691/

• Anti-Inflammatory Effects of Ethanol Extract of Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes), in Mice with Ulcerative Colitis

 https://pubmed.ncbi.nlm.nih.gov/27481156/

• Can medicinal mushrooms have prophylactic or therapeutic effect against COVID-19 and its pneumonic superinfection and complicating inflammation?

 https://pubmed.ncbi.nlm.nih.gov/32657436/